Advertisement
Review Article|Articles in Press

Pulmonary Metastasectomy

Indications, Best Practices, and Evolving Role in the Future
Published:February 26, 2023DOI:https://doi.org/10.1016/j.thorsurg.2023.01.004

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Thoracic Surgery Clinics
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Corsini E.M.
        • Antonoff M.B.
        Is pulmonary metastasectomy effective in prolonging survival?.
        in: Ferguson M.K. Difficult decisions in thoracic surgery: an evidence-based approach. Springer International Publishing, New York, NY2020: 279-289
        • Cheung F.P.-Y.
        • Alam N.Z.
        • Wright G.M.
        The past, present and future of pulmonary metastasectomy: a review article.
        Ann Thorac Cardiovasc Surg. 2019; 25: 129-141
        • Jamil A.
        • Kasi A.
        Lung metastasis. StatPearls.
        in: StatPearls Publishing Copyright ©2022. StatPearls Publishing LLC, Tampa, FL2022
        • Petrella F.
        • Diotti C.
        • Rimessi A.
        • et al.
        Pulmonary metastasectomy: an overview.
        J Thorac Dis. 2017; 9: S1291-S1298
        • Schweiger T.
        • Lang G.
        • Klepetko W.
        • et al.
        Prognostic factors in pulmonary metastasectomy: spotlight on molecular and radiological markers.
        Eur J Cardio Thorac Surg. 2014; 45: 408-416
        • Antonoff M.B.
        • Sofocleous C.T.
        • Callstrom M.R.
        • et al.
        The roles of surgery, stereotactic radiation, and ablation for treatment of pulmonary metastases.
        J Thorac Cardiovasc Surg. 2022; 163: 495-502
        • Handy J.R.
        • Bremner R.M.
        • Crocenzi T.S.
        • et al.
        Expert consensus document on pulmonary metastasectomy.
        Ann Thorac Surg. 2019; 107: 631-649
        • Erhunmwunsee L.
        • Tong B.C.
        Preoperative evaluation and indications for pulmonary metastasectomy.
        Thorac Surg Clin. 2016; 26: 7-12
        • Blackmon S.H.
        • Stephens E.H.
        • Correa A.M.
        • et al.
        Predictors of recurrent pulmonary metastases and survival after pulmonary metastasectomy for colorectal cancer.
        Ann Thorac Surg. 2012; 94: 1802-1809
        • Nichols F.C.
        Pulmonary metastasectomy: role of pulmonary metastasectomy and type of surgery.
        Curr Treat Options Oncol. 2014; 15: 465-475
        • Chandy E.T.J.
        • Saxby H.J.
        • Pang J.W.
        • et al.
        The multidisciplinary management of oligometastases from colorectal cancer: a narrative review.
        Ann Palliat Med. 2020; 10: 5988-6001
        • Brunelli A.M.D.
        • Socci L.M.D.
        • Refai M.M.D.
        • et al.
        Quality of life before and after major lung resection for lung cancer: a prospective follow-up analysis.
        Ann Thorac Surg. 2007; 84: 410-416
        • Chua T.C.
        • Thornbury K.
        • Saxena A.
        • et al.
        Radiofrequency ablation as an adjunct to systemic chemotherapy for colorectal pulmonary metastases.
        Cancer. 2010; 116: 2106-2114
        • Treasure T.
        • Farewell V.
        • Macbeth F.
        • et al.
        Pulmonary metastasectomy versus continued active monitoring in colorectal cancer (PulMiCC): a multicentre randomised clinical trial.
        Trials. 2019; 20: 718
        • Antonoff M.B.
        Registered Clinical Trial: Chemotherapy and/or metastasectomy in treating patients with metastatic colorectal adenocarcinoma with lung metastases. 2022; NCT03599752
        • Cho J.H.M.D.
        • Hamaji M.M.D.
        • Allen M.S.M.D.
        • et al.
        The prognosis of pulmonary metastasectomy depends on the location of the primary colorectal cancer.
        Ann Thorac Surg. 2014; 98: 1231-1237
        • Chudgar N.P.M.D.
        • Brennan M.F.M.D.
        • Munhoz R.R.M.D.
        • et al.
        Pulmonary metastasectomy with therapeutic intent for soft-tissue sarcoma.
        J Thorac Cardiovasc Surg. 2017; 154: 319-330.e1
        • Farazdaghi A.
        • Vaughn D.J.
        • Singhal S.
        Pulmonary metastasectomy for germ cell tumors.
        Ann Thorac Cardiovasc Surg. 2019; : ra.19-00070https://doi.org/10.5761/atcs.ra.19-00070
        • Hanna T.P.
        • Chauvin C.
        • Miao Q.
        • et al.
        Clinical outcomes after pulmonary metastasectomy for melanoma: a population-based study.
        Ann Thorac Surg. 2018; 106: 1675-1681
        • Liu Z.
        • Yin J.
        • Zhou Q.
        • et al.
        Survival after pulmonary metastasectomy for relapsed osteosarcoma.
        J Thorac Cardiovasc Surg. 2022; 163: 469-479.e8
        • Doty J.R.
        • Vricella L.A.
        • Yang S.C.
        • et al.
        Johns Hopkins textbook of cardiothoracic surgery. 2nd edition. McGraw-Hill’s AccessMedicine. McGraw Hill Medical, New York, NY2007
        • Yun J.S.
        • Kim E.
        • Na K.J.
        • et al.
        Thoracoscopic pulmonary metastasectomy in metastatic colorectal cancer: surgical outcomes and prognostic factors.
        Thorac Cancer. 2021; 12: 2537-2543
        • Dickinson K.J.
        • Blackmon S.H.
        Results of pulmonary resection: colorectal carcinoma.
        Thorac Surg Clin. 2016; 26: 41-47
        • Labianca R.
        • Beretta G.D.
        • Kildani B.
        • et al.
        Colon cancer.
        Crit Rev Oncol Hematol. 2010; 74: 106-133
        • Corsini E.M.
        • Mitchell K.G.
        • Correa A.
        • et al.
        Effect of primary colorectal cancer tumor location on survival after pulmonary metastasectomy.
        J Thorac Cardiovasc Surg. 2021; 162: 296-305
        • Gusho C.A.
        • Seder C.W.
        • Lopez-Hisijos N.
        • et al.
        Pulmonary metastasectomy in bone and soft tissue sarcoma with metastasis to the lung.
        Interact Cardiovasc Thorac Surg. 2021; 33: 879-884
        • Ouzaid I.
        • Capitanio U.
        • Staehler M.
        • et al.
        Surgical metastasectomy in renal cell carcinoma: a systematic review.
        Eur Urol Oncol. 2019; 2: 141-149
        • Milosevic M.
        • Edwards J.
        • Tsang D.
        • et al.
        Pulmonary metastasectomy in colorectal cancer: updated analysis of 93 randomized patients – control survival is much better than previously assumed.
        Colorectal Dis. 2020; 22: 1314-1324
        • Greenwood A.
        • West D.
        Is a thoracotomy rather than thoracoscopic resection associated with improved survival after pulmonary metastasectomy?.
        Interact Cardiovasc Thorac Surg. 2013; 17: 720-724
        • Lumachi F.
        • Mazza F.
        • Del Conte A.
        • et al.
        Factors affecting survival in patients with pulmonary metastases from colorectal cancer with previously resected liver metastases who underwent lung metastasectomy.
        Ann Oncol. 2015; 26: i45
        • Gonzalez M.
        • Poncet A.
        • Combescure C.
        • et al.
        Risk factors for survival after lung metastasectomy in colorectal cancer patients: a systematic review and meta-analysis.
        Ann Surg Oncol. 2012; 20: 572-579
        • Zabaleta J.
        • Iida T.
        • Falcoz P.E.
        • et al.
        Individual data meta-analysis for the study of survival after pulmonary metastasectomy in colorectal cancer patients: a history of resected liver metastases worsens the prognosis.
        Eur J Surg Oncol. 2018; 44: 1006-1012
        • Corsini E.M.
        • Mitchell K.G.
        • Mehran R.J.
        • et al.
        Colorectal cancer mutations are associated with survival and recurrence after pulmonary metastasectomy.
        J Surg Oncol. 2019; 120: 729-735
        • Marulli G.
        • Mammana M.
        • Comacchio G.
        • et al.
        Survival and prognostic factors following pulmonary metastasectomy for sarcoma.
        J Thorac Dis. 2017; 9: S1305-S1315
        • Ripley R.T.
        • Downey R.J.
        Pulmonary metastasectomy.
        J Surg Oncol. 2014; 109: 42-46
        • Zhao Y.
        • Li J.
        • Li C.
        • et al.
        Prognostic factors for overall survival after lung metastasectomy in renal cell cancer patients: a systematic review and meta-analysis.
        Int J Surg. 2017; 41: 70-77
        • Marincola F.M.
        • White D.E.
        • Wise A.P.
        • et al.
        Combination therapy with interferon alfa-2a and interleukin-2 for the treatment of metastatic cancer.
        J Clin Oncol. May 1995; 13: 1110-1122
        • Sandru A.
        • Voinea S.
        • Panaitescu E.
        • et al.
        Survival rates of patients with metastatic malignant melanoma.
        J Med Life. 2014; 7: 572-576
        • Krege S.
        • Beyer J.
        • Souchon R.
        • et al.
        European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): Part II.
        Eur Urol. 2008; 53: 497-513
        • Krüger M.
        • Schmitto J.D.
        • Wiegmann B.
        • et al.
        Optimal timing of pulmonary metastasectomy: is a delayed operation beneficial or counterproductive?.
        Eur J Surg Oncol. 2014; 40: 1049-1055
        • Yamada K.
        • Ozawa D.
        • Onozato R.
        • et al.
        Optimal timing for the resection of pulmonary metastases in patients with colorectal cancer.
        Medicine (Baltim). 2020; 99: e19144
        • Ahmed G.
        • Zamzam M.
        • Kamel A.
        • et al.
        Effect of timing of pulmonary metastasis occurrence on the outcome of metastasectomy in osteosarcoma patients.
        J Pediatr Surg. 2019; 54: 775-779
        • Eckardt J.M.D.
        • Licht P.B.M.D.P.
        Thoracoscopic or open surgery for pulmonary metastasectomy: an observer blinded study.
        Ann Thorac Surg. 2014; 98: 466-470
        • Macherey S.
        • Doerr F.
        • Heldwein M.
        • et al.
        Is manual palpation of the lung necessary in patients undergoing pulmonary metastasectomy?.
        Interact Cardiovasc Thorac Surg. 2016; 22: 351-359
        • Cerfolio R.J.
        • McCarty T.
        • Bryant A.S.
        Non-imaged pulmonary nodules discovered during thoracotomy for metastasectomy by lung palpation.
        Eur J Cardio Thorac Surg. 2009; 35: 786-791
        • Lo Faso F.
        • Solaini L.
        • Lembo R.
        • et al.
        Thoracoscopic lung metastasectomies: a 10-year, single-center experience.
        Surg Endosc. 2013; 27: 1938-1944
        • Van Haren R.M.
        • Mehran R.J.
        • Mena G.E.
        • et al.
        Enhanced recovery decreases pulmonary and cardiac complications after thoracotomy for lung cancer.
        Ann Thorac Surg. 2018; 106: 272-279
        • Feldman H.A.
        • Zhou N.
        • Antonoff M.B.
        • et al.
        Simultaneous versus staged resections for bilateral pulmonary metastases.
        J Surg Oncol. 2021; 123: 1633-1639
        • McKenna J.R.J.
        Surgical management of primary lung cancer.
        Semin Oncol. 2007; 34: 250-255
        • Phillips J.D.
        • Hasson R.M.
        Surgical management of colorectal lung metastases.
        J Surg Oncol. 2019; 119: 629-635
        • Nelson D.B.
        • Tayob N.
        • Mitchell K.G.
        • et al.
        Surgical margins and risk of local recurrence after wedge resection of colorectal pulmonary metastases.
        J Thorac Cardiovasc Surg. 2019; 157: 1648-1655
        • Strand T.E.
        • Rostad H.
        • Damhuis R.A.
        • et al.
        Risk factors for 30-day mortality after resection of lung cancer and prediction of their magnitude.
        Thorax. 2007; 62: 991-997
        • Treasure T.
        • Dunning J.
        • Williams N.R.
        • et al.
        Lung metastasectomy for colorectal cancer: the impression of benefit from uncontrolled studies was not supported in a randomized controlled trial.
        J Thorac Cardiovasc Surg. 2022; 163: 486-490
        • Seebacher G.M.D.
        • Decker S.M.D.
        • Fischer J.R.M.D.
        • et al.
        Unexpected lymph node disease in resections for pulmonary metastases.
        Ann Thorac Surg. 2015; 99: 231-236
        • Ambrogi V.
        • Tamburrini A.
        • Tajé R.
        Results of redo pulmonary metastasectomy.
        J Thorac Dis. 2021; 13: 2669-2685
        • Krüger M.
        • Franzke K.
        • Rajab T.K.
        • et al.
        Outcome of repeat pulmonary metastasectomy.
        Adv Exp Med Biol. 2021; 1335: 37-44
        • Mills A.C.
        Repeat pulmonary metastasectomy: third operations and beyond.
        Ann Thorac Surg. 2022; https://doi.org/10.1016/j.athoracsur.2022.07.025
        • Nguyenhuy M.
        • Xu Y.
        • Maingard J.
        • et al.
        A systematic review and meta-analysis of patient survival and disease recurrence following percutaneous ablation of pulmonary metastasis.
        Cardiovasc Intervent Radiol. 2022; 45: 1102-1113