Thoracic Surgery Clinics
Volume 19, Issue 1 , Pages 71-81, February 2009

Multimodality Treatment of Thymic Tumors

  • Federico Venuta, MD

      Affiliations

    • Department of Thoracic Surgery, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy
    • Lung Transplantation Unit, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy
    • Corresponding Author InformationCorresponding author.
  • ,
  • Erino A. Rendina, MD

      Affiliations

    • Thoracic Surgery Unit, University of Rome Sapienza, Ospedale S. Andrea, Rome, Italy
  • ,
  • Giorgio F. Coloni, MD

      Affiliations

    • Thoracic Surgery Unit, Department of Surgery, University of Rome Sapienza, Policlinico Umberto I, Rome, Italy

Tumors of the thymus are rather infrequent compared with all the other thoracic neoplasms. They may display a variable clinical presentation and outcome. Although they may present as a capsulated lesion with an indolent course, in other cases they may be locally aggressive, invading the surrounding structures, or show the presence of distant metastases. At these advanced stages, cure and complete resection may be difficult, and only a multimodality approach integrating surgery with induction chemotherapy and adjuvant treatment can contribute to improve outcome.

Keywords: Thymoma, Mediastinal tumors, Superior vena cava syndrome, Chemotherapy, Radiotherapy, Mulitmodality therapy

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PII: S1547-4127(08)00083-2

doi:10.1016/j.thorsurg.2008.09.008

Thoracic Surgery Clinics
Volume 19, Issue 1 , Pages 71-81, February 2009